605 days, 16 hours, 0 minutes, 40 seconds

Two years ago? Three years ago? The friend of a friend called to warn her that her friend was freaking out, crashing at her country home, not answering the phone, not taking care of the animals as promised. And this friend might well be headed in our narrator's direction. A few days after that the friend called, not knowing how to explain the call, except she's learned that this friend at whose house she was crashing has a brain tumor. Hence the personality changes.